Intermittent Fasting for Women: What the Research Shows
In trials, intermittent fasting gives similar weight loss to an ordinary calorie deficit. On 16:8, menopause, PCOS, pregnancy and who should avoid fasting.
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Download SmakligShort answer: In trials, intermittent fasting gives roughly the same weight loss as an ordinary calorie deficit. Pregnant and breastfeeding women, people under 18, anyone who has or has had an eating disorder and anyone taking insulin or sulfonylureas should not fast on their own.
- Cochrane 2026: 22 randomised trials with 1,995 participants showed little or no difference from standard dietary advice (−0.33 percentage points of weight loss)
- NEJM 2022: an eating window plus a calorie target gave −8.0 kg against −6.3 kg with a calorie target alone over 12 months, with no significant difference
- Women with overweight or obesity: in 13 randomised trials with 612 participants, at least 85% of them women, an eating window gave no advantage over calorie restriction in a subanalysis (Chen 2025)
- Hormones: no effect on oestrogen in women, but very few studies (Cienfuegos 2022)
- Pregnancy: there are no randomised trials; all 19 studies in a meta-analysis were observational (Giorno 2025)
Intermittent fasting for women is one of the most talked-about ways to lose weight, and many women wonder whether it works differently for them. Perhaps you have heard that fasting affects your periods, that it helps during the menopause or that it is especially good for PCOS. This article goes through what the studies actually show, which groups have been studied and where the knowledge runs out. It is not a guide to doing it and contains no schedules. The Swedish Food Agency (Livsmedelsverket) sums up the evidence like this: "There does not seem to be any difference in weight loss between cutting calories on certain days and reducing energy intake a little every day" (our translation, Livsmedelsverket, Diets).

What is intermittent fasting?#
Intermittent fasting is an umbrella term for approaches that alternate between periods of eating and periods of eating little or nothing. The most common forms in research are 16:8, where all food is eaten within an 8-hour eating window, 5:2, where you eat 500–600 kcal on two days a week, and alternate-day fasting. What they have in common is that they govern when you eat, not what.
The terms are used slightly differently in studies and in popular books. In the TREAT trial, 16:8 meant an eating window of 8 hours a day (Lowe 2020). In a diabetes trial, 5:2 meant participants ate 500–600 kcal on two days a week and as usual for the rest of the week (Carter 2018). Alternate-day fasting means fasting days and normal days take turns.
The Swedish Food Agency also points out that "the evidence for saying anything about effects other than weight loss in humans is insufficient" (our translation, Livsmedelsverket). That is worth keeping in mind when you read about fasting's claimed effects on hormones, metabolism or ageing.
Do you lose more weight with intermittent fasting?#
No, not according to the studies so far. Intermittent fasting does lead to weight loss, but about as much as an ordinary calorie deficit. The 2026 Cochrane review covers 22 randomised trials with 1,995 adults with overweight or obesity. It found little or no difference compared with standard dietary advice: the difference in weight loss was 0.33 percentage points (21 trials, 1,430 participants), and the certainty of the evidence was rated as low (Garegnani 2026).
A randomised trial from China had a calorie target in both groups. 139 adults with obesity ate to a calorie target for 12 months, and half of them also ate within an 8-hour window. The fasting group lost 8.0 kg and the calorie group 6.3 kg. The difference of 1.8 kg was not statistically significant (P = 0.11) (Liu 2022, NEJM). The trial gave the women 1,200–1,500 kcal a day as part of its design. That is not a recommendation. What a reasonable deficit looks like for you is covered in our guide to how big a calorie deficit needs to be.
The BMJ network meta-analysis from 2025 (99 randomised trials, 6,582 adults) compared several forms against each other. Alternate-day fasting was the only form that gave a small advantage over daily calorie restriction, −1.29 kg, and only in trials shorter than 24 weeks (Semnani-Azad 2025). The conclusion is that fasting is one way of eating less, not a shortcut.
How long the result lasts is not known. The trials in the Cochrane review followed participants for 12 months at most. What affects your weight after weight loss is covered in the article on stabilisation after weight loss.
Intermittent fasting compared with an ordinary calorie deficit: what the studies show#
The table shows the most important studies side by side. The comparison group differs between the studies and is given in the column. In every comparison, the difference was small or not significant. Note the populations: TREAT was 60% men, Carter covered people with type 2 diabetes and Liu Chinese adults with obesity. Only Chen and Corapi studied women: Corapi only women, Chen trials in which at least 85% were women.
| Approach | Study (type, size, length) | Weight result | Difference from the comparison group | Source |
|---|---|---|---|---|
| All forms of intermittent fasting | Cochrane review, 22 RCTs, 1,995 people, up to 12 months | −0.33 percentage points against standard dietary advice | No meaningful difference (low certainty) | Garegnani 2026 |
| Alternate-day fasting | Network meta-analysis, 99 RCTs, 6,582 people | −1.29 kg against daily restriction | Small advantage, only in trials under 24 weeks | Semnani-Azad 2025 |
| 8-hour eating window plus calorie target | RCT, 139 Chinese adults with obesity, 12 months | −8.0 against −6.3 kg | Not significant (−1.8 kg; P = 0.11) | Liu 2022 |
| 16:8 without calorie target | RCT, 116 people (60% men), 12 weeks | −0.94 kg against −0.68 kg (three meals a day) | Not significant (−0.26 kg) | Lowe 2020 |
| 5:2 (500–600 kcal on two days), type 2 diabetes | RCT, 137 people (77 women), 12 months | −6.8 against −5.0 kg | Not significant (P = 0.25) | Carter 2018 |
| Eating window, mainly women with overweight or obesity | Meta-analysis, 13 RCTs, 612 people (at least 85% women) | −1.93 kg against control | No advantage over calorie restriction in a subanalysis (p = 0.295) | Chen 2025 |
| 6-hour eating window, PCOS | RCT, 76 women, 6 months | −4.32% against −4.66% (calorie restriction), both compared with the control group | Both vs control: P < 0.01; eating window vs calorie restriction: not significant (0.34 percentage points, P = 0.79) | Corapi 2026 |
The TREAT trial fits the pattern. There, estimated energy intake did not differ between the groups, and neither did weight loss (Lowe 2020). The studies therefore suggest that how much you eat over time matters more than the clock.
Does intermittent fasting affect the menstrual cycle and hormones?#
There is too little research to say for certain. A review of human trials found that fasting "did not have any effect on estrogen, gonadotropins, or prolactin levels in women", but the authors also write that there are "very few studies" and that firm conclusions are hard to draw (Cienfuegos 2022). In premenopausal women with obesity, androgen markers fell and SHBG rose.
There are animal studies where an 8-hour eating window in animals of normal weight "may have adverse effects on reproductive function" (Mao 2024). This has not been shown in humans and cannot be transferred directly. The opposite claim, that fasting is especially good for women's hormones, has no support either.
What is known with more confidence concerns energy as a whole. If your periods become irregular or stop when you eat less, that is a signal to contact your GP. Why too large a deficit can affect your periods, and what energy availability means, is explained in the article on calorie deficits for women.
Intermittent fasting during the menopause: what is known?#

Very little. Many women thinking about their weight during the menopause come across fasting as a suggestion, but the research is thin. A systematic review of 15 randomised trials on diet for menopausal symptoms found that the evidence for intermittent fasting is limited and concerns cognition, not hot flushes (O'Neill 2026). There is no evidence that fasting relieves menopausal symptoms.
A small pilot study of 25 postmenopausal women compared two ways of cutting calories: five-week periods of calorie restriction alternating with five weeks of weight stabilisation, against continuous restriction. Weight loss was similar in both groups (Arguin 2012). These were diet breaks, not fasting within the day or week, so the study says nothing about 16:8 or 5:2 during the menopause. For weight during the menopause the same principle applies as at any other time: it is your total intake over the week that counts.
Does intermittent fasting help with PCOS?#
As well as calorie restriction, but not better, according to a randomised trial from 2026. 76 women with PCOS were followed for 6 months. Compared with the control group, which did not change its diet, the group with a 6-hour eating window lost 4.32 percentage points more of their body weight and the group on 25% calorie restriction 4.66 points more. The difference of 0.34 percentage points between the two was not significant (P = 0.79) (Corapi 2026, Nature Medicine).
A meta-analysis of five studies compared values before and after fasting, without a control group. Weight fell by 4.25 kg, the free androgen index (FAI) by 1.61 percentage points, and SHBG rose. The authors write that the evidence is still "preliminary" (Ranneh 2025).
Worth knowing: the Corapi trial and the Cienfuegos review come from the same research group, and according to the Nature Medicine paper co-author Krista A. Varady receives fees from publishers for books on fasting diets. That does not make the results wrong, but it is a reason not to base conclusions on a single study. PCOS is treated individually, so talk to your doctor before you change your diet.
Can you fast while pregnant or breastfeeding?#
There is no randomised trial of fasting during pregnancy. A meta-analysis found 19 studies, mainly on Ramadan fasting, and all were observational. Fasting was associated with an average birth weight 94 g lower, but not with a higher risk of low birth weight (RR 0.96) (Giorno 2025). An umbrella review concludes that clinicians "cannot provide firm recommendations" (Al-Taiar 2025).
Fasting during pregnancy has therefore been shown neither safe nor harmful; it simply has not been studied in randomised trials. Avoid it and ask your midwife.
For breastfeeding, the Swedish Food Agency advises: "On average, a breastfeeding mother needs about 500 extra kilocalories a day." The agency also writes that "a good goal is to return to your pre-pregnancy weight within about a year" (our translation, Livsmedelsverket, Breastfeeding). If you want to lose weight while breastfeeding, your midwife or GP is the right person to talk to.
Who should not fast?#
Pregnant and breastfeeding women, people under 18, anyone who has or has had an eating disorder, and anyone with diabetes who takes insulin or sulfonylureas without their doctor involved. For these groups there are either no randomised trials, or known risks that require healthcare to be involved.
The diabetes risk is concrete. In a 5:2 trial of 137 people with type 2 diabetes, medication that can cause low blood sugar was reduced from the start. Even so, 16 of 46 people taking sulfonylureas or insulin (35%) had hypo- or hyperglycaemia during the first two weeks. The figure covers both groups together, 5:2 and daily calorie restriction, and the number of events did not differ significantly between them (Carter 2018). A trial of 46 people with insulin-treated type 2 diabetes saw no severe hypoglycaemia over 12 weeks, but participants had dietary counselling and continuous glucose monitoring (Obermayer 2023). This suggests that fasting while on diabetes medication should only be done with your doctor.
The link to eating disorders has not been shown to be causal, but it exists. Among 2,762 Canadian adolescents and young adults, 47.7% of the female participants reported fasting in the past year, and fasting was associated with more eating disorder symptoms (Ganson 2022, cross-sectional study). In a Chinese follow-up of 491 adults over 8 months, fasting was associated with more eating disorder symptoms at follow-up (He 2025). If you have a difficult relationship with food, you do not have to handle it alone: talk to your GP or contact the National Alliance for Eating Disorders.
Can you drink black coffee while fasting?#
Black coffee provides almost no energy. According to Swedish Food Agency (Livsmedelsverket) values from its food composition database, brewed coffee contains 2 kcal and 0.0 g protein per 100 g, and espresso 9 kcal and 0.1 g protein per 100 g. It is milk, cream and sugar that provide the energy. Whether it "breaks the fast" depends on how you define the fast, not on a physiological limit.
None of the studies in this review compares coffee with and without additions during fasting. Claims that black coffee strengthens fasting's effects on blood sugar or fat metabolism are therefore not supported by them. The simple answer is that black coffee adds no energy worth mentioning, while a caffè latte does.
Do you lose muscle with intermittent fasting?#

The results point in different directions. In the TREAT trial (12 weeks), body composition was measured in a subgroup of 50 people, 25 in each group. There, a height-adjusted index of lean mass in the arms and legs fell more in the fasting group than in the control group, by 0.16 kg/m² (Lowe 2020). Chen's meta-analysis of 13 randomised trials, in which at least 85% of participants were women with overweight or obesity, by contrast found no statistically significant difference from the control groups in lean mass (Chen 2025).
Why the studies differ has not been explained. One possibility, which the studies have not tested, is how much protein participants ate: fewer meals can mean less protein if you do not pay attention to it. How to get protein in early in the day is described in the article on a high-protein breakfast for weight loss.
How Smaklig fits in#
Smaklig does not offer a fasting diet, and there is no need for one. The studies suggest that what matters is what and how much you eat over the week, not the clock. That is why Smaklig plans the week's dinners around the offers in the shop where you buy your food, across all seven Swedish chains the app follows, and writes the shopping list for you. If you shop at ICA or Coop, the items can go straight into your basket in the app. Whether you eat three meals a day or within a shorter window, a planned week helps you get nourishing meals without starting from scratch every evening. More on how planning helps with weight loss is in the guide to weight loss with meal planning.
The app works out a daily target for calories and protein from your weight, your goal and how active you are, and every recipe shows protein per portion. That makes it easier to see whether the day's meals give you enough protein, even when there are fewer of them. If a dinner doesn't suit you, you replace the recipe, and if more or fewer people eat, you change the number of portions. If any of the situations above apply to you, such as pregnancy, breastfeeding or treatment with insulin or sulfonylureas, your GP's or midwife's advice comes before the app's suggestions.
Common mistakes#
- Believing the eating window itself gives extra weight loss. The effect comes from eating less, not from the clock (Garegnani 2026, Liu 2022).
- Assuming the eating window works on its own. In TREAT, neither estimated energy intake nor weight loss differed between the groups.
- Fasting during pregnancy, breastfeeding or diabetes medication without healthcare involved. There are either no randomised trials or known risks.
- Reading missed periods as the body "adjusting". It is a signal to contact your GP.
- Trusting promises that fasting cleanses the body or regulates hormones. Such effects are not found in the studies.
- Letting protein slip when the number of meals falls. In the TREAT subgroup, the lean mass index for arms and legs fell more in the fasting group.
Checklist#
- Ask yourself first: are you pregnant, breastfeeding, under 18, do you have or have you had an eating disorder, or do you take insulin or sulfonylureas? Then your GP or midwife is the right first step, not fasting on your own.
- Compare with the alternative: a steady, moderate deficit gives the same results as fasting in trials.
- Think about content: protein, vegetables and wholegrains matter whenever you eat.
- Listen to your body: if your periods stop, or food starts to cause anxiety, it is time to seek support, for example from your GP.
- Choose what you can live with: the Swedish Food Agency writes that the most important thing is that a diet "can be kept up over a longer period" (our translation).
- Plan the week: a weekly plan with protein per portion makes it easier to eat well, whatever time of day you eat.
Sources
- Cochrane Database of Systematic Reviews. Garegnani L et al. — Intermittent fasting for adults with overweight or obesity (2026)
- BMJ. Semnani-Azad Z et al. — Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials (2025)
- New England Journal of Medicine. Liu D et al. — Calorie Restriction with or without Time-Restricted Eating in Weight Loss (2022)
- JAMA Internal Medicine. Lowe DA et al. — Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial (2020)
- Frontiers in Nutrition. Chen et al. — Effects of time-restricted eating on body composition and metabolic parameters in overweight and obese women: a systematic review and meta-analysis (2025)
- Nature Medicine. Corapi et al. — Time-restricted eating for body weight management in women with polycystic ovary syndrome: a randomized controlled trial (2026)
- Nutrients. Cienfuegos S et al. — Effect of Intermittent Fasting on Reproductive Hormone Levels in Females and Males: A Review of Human Trials (2022)
- Nutrients. Giorno et al. — Intermittent Fasting During Pregnancy and Neonatal Birth Weight: A Systematic Review and Meta-Analysis (2025)
- International Journal of Gynecology & Obstetrics. Al-Taiar et al. — Impacts of Ramadan fasting during pregnancy on pregnancy and birth outcomes: An umbrella review (2025)
- Eating Behaviors. Ganson KT et al. — Intermittent fasting: Describing engagement and associations with eating disorder behaviors and psychopathology among Canadian adolescents and young adults (2022)
- International Journal of Eating Disorders. He et al. — Engagement in Intermittent Fasting is Prospectively Associated With Higher Body Mass Index, Higher Eating Disorder Psychopathology, and Lower Intuitive Eating in Chinese Adults (2025)
- JAMA Network Open. Carter S et al. — Effect of Intermittent Compared With Continuous Energy Restricted Diet on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Noninferiority Trial (2018)
- Nutrients. Ranneh et al. — Effect of Intermittent Fasting on Anthropometric Measurements, Metabolic Profile, and Hormones in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis (2025)
- American Journal of Clinical Nutrition. O'Neill et al. — Dietary interventions for menopausal symptoms: a systematic review (2026)
- Menopause. Arguin H et al. — Short- and long-term effects of continuous versus intermittent restrictive diet approaches on body composition and the metabolic profile in overweight and obese postmenopausal women: a pilot study (2012)
- Diabetes Care. Obermayer A et al. — Efficacy and Safety of Intermittent Fasting in People With Insulin-Treated Type 2 Diabetes (INTERFAST-2)-A Randomized Controlled Trial (2023)
- Current Nutrition Reports. Mao et al. — Effects of Intermittent Fasting on Female Reproductive Function: A Review of Animal and Human Studies (2024)
- Livsmedelsverket (Swedish Food Agency). Livsmedelsdatabasen, näringsvärden för kaffe bryggt (API, version 20260701) (Swedish food composition database: nutritional values for brewed coffee, in Swedish)
- Livsmedelsverket (Swedish Food Agency). Dieter: periodisk fasta och halvfasta (Diets: intermittent fasting and partial fasting, in Swedish)
- Livsmedelsverket (Swedish Food Agency). Ammande – hur mycket mat är lagom? (Breastfeeding: how much food is right?, in Swedish)
Frequently asked questions
Is 16:8 better for women than 5:2?
It has not been shown that 16:8 is better than 5:2 for women. In the BMJ network meta-analysis from 2025 (99 randomised trials, 6,582 adults), neither time-restricted eating nor whole-day fasting differed from ordinary daily calorie restriction. Only alternate-day fasting gave a small advantage of 1.29 kg, and only in trials shorter than 24 weeks.
Can intermittent fasting cause irregular periods?
It is not possible to say for certain. A review of human trials (Cienfuegos 2022) found no effect on oestrogen, gonadotropins or prolactin in women, but the authors note that there are very few studies. If your periods stop or become irregular when you eat less, that is a signal to contact your GP, not something your body should get used to.
Can you fast while breastfeeding?
There are no randomised trials of fasting during breastfeeding. The Swedish Food Agency states that breastfeeding mothers need on average about 500 extra kilocalories a day, and that a good goal is to return to your pre-pregnancy weight within about a year. If you want to change how you eat while breastfeeding, talk to your midwife or GP first.
Does intermittent fasting help with PCOS?
In a randomised trial (76 women with PCOS, 6 months, Nature Medicine 2026), women with a 6-hour eating window lost 4.32 percentage points more of their body weight than the control group, and those on 25% calorie restriction 4.66 points more. The difference between fasting and calorie restriction was not significant. A meta-analysis of five studies, which compared values before and after fasting without a control group, saw improved androgen markers but calls the evidence preliminary. Talk to your doctor about your treatment.
Can you fast if you have diabetes?
With insulin or sulfonylureas there is a risk of low blood sugar. In a one-year trial in people with type 2 diabetes, where medication was reduced according to protocol, 16 of 46 people taking such medication (35%) had hypo- or hyperglycaemia during the first two weeks. The figure covers both groups together, 5:2 and daily calorie restriction, and did not differ between them. Fasting while on diabetes medication should only be done together with a doctor who adjusts the treatment.
Who should not fast?
Pregnant and breastfeeding women, people under 18, anyone who has or has had an eating disorder, and anyone with diabetes who takes insulin or sulfonylureas without their doctor involved. For these groups there are either no randomised trials or known risks. If you have a difficult relationship with food, your GP or the National Alliance for Eating Disorders can offer support.
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Writer at Smaklig. We write about food, health, and how to eat better without breaking the bank.
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